A professor of entrepreneurship at several European business schools, Jean-Jacques Degroof has also mentored several young tech entrepreneurs. Jean-Jacques Degroof holds a PhD in management from the Massachusetts Institute of Technology (MIT) Sloan School of Management, where he has served as a researcher and supported the Aging Brain Initiative, which recently published an article on new research regarding a gene related to familial amyotrophic lateral sclerosis (ALS).
MIT biologists have identified a specific gene that they believe may prevent neurons from getting rid of waste, which may lead to some symptoms of ALS. Their research is based on a study of Caenorhabditis elegans, a microscopic worm that experiences buildup of unwanted substances inside its cells when the gene in question is mutated. This buildup occurs because mutation causes defects in lysosomes, structures that usually eliminate waste.
Researchers believe that this function of this specific gene may cause as many as 40 percent of familial cases of ALS, as studies have shown that an enlarged DNA region in an area of this gene can lead to the disease. This research represents a step forward in the body of knowledge regarding the role of genetics in ALS. The success of future treatments may rely on research focused on drugs that can reduce genetic mutations while maintaining lysosome homeostasis.
With more than 17 years of experience as a venture investor, Jean-Jacques Degroof teaches entrepreneurship at several business schools in Europe. Jean-Jacques Degroof holds a PhD in management from the Massachusetts Institute of Technology (MIT) Sloan School of Management, which has developed a new course titled Blockchain and Money.
Led by Gary Gensler, a former wall street regulator and Goldman Sachs partner, Blockchain and Money is designed to introduce students to the world of blockchain, which has the potential to make a significant impact on the financial sector. The course looks at bitcoin, the first major cryptocurrency, and requires students to read Bitcoin: A Peer-to-Peer Electronic Cash System, by Satoshi Nakamoto, the name used by the unknown person or group that developed the currency.
The new MIT course also introduces students to smart contracts and distributed ledgers, which are vital to blockchain technology. Moving beyond theory, the course explores real-world applications of blockchain technology in the financial industry and in payment systems in several countries, including the United States, the United Kingdom, China, and Kenya.
Alongside his work in venture investing, Jean-Jacques Degroof serves as an international lecturer on topics such as innovation management and entrepreneurship. A graduate of the Sloan School of Management at the Massachusetts Institute of Technology (MIT), Jean-Jacques Degroof continues to support the school and its research endeavors.
MIT recently completed a study led by Prof. Li-Huei Tsai on the gene known as APOE4, which is associated with Alzheimer’s disease and the buildup of amyloid proteins called plaque in the brain. The study sought to compare this gene with its more common expression, APOE3, by examining brain cells developed from human stem cells.
Previous studies had identified significantly increased amounts of amyloid proteins in people with the APOE4 gene variant. In the recent study, MIT neuroscientists sought to discover the cause of that difference by evaluating genes of identical genetic material with the exception of the APOE4 and APOE3 gene. They compared these genes in three different types of brain cells.
The researchers found differences ranging from dysregulation of cholesterol metabolism to increased formation of synapses in the APOE4 gene versus the standard APOE3 gene. Researchers also succeeded in reversing many of these differences in brain cells from a patient with Alzheimer's disease by substituting the regular gene for the variant.
Jean-Jacques Degroof, a self-employed venture investor, mentor, and teacher of entrepreneurship and investment management, is a frequent participant in the Charite Entrepreneurship Summit. During the events from 2013 through 2015, Jean-Jacques Degroof was a member of the summit's advisory group, which helps to organize the conference.
Sponsored principally by the Berlin Institute of Health (BIH), the Charite BIH Entrepreneurship Summit hosts hundreds of global leaders in the healthcare field including scientists, entrepreneurs, lawmakers, and investors. These thought leaders come from all over the world and representatives from Europe, Australia, North America, and Israel have participated in the event over its existence. This event has been held for more than a decade, partnering with different countries to highlight their contributions to the field.
The 2018 Summit will be held in May, and will include topics from areas including healthcare technology, experimental research, and investment. It will also include the Life Sciences Venture Market, in which companies can present their findings to potential investors and collaborators in order to seek funding, advice, and interpersonal connections.
A mentor and educator, Jean-Jacques Degroof earned degrees in organizational behavior and business administration from the Catholic University of Louvain and a Ph.D. in Management from the Massachusetts Institute of Technology (MIT). Now teaching entrepreneurship to business students across Europe, Jean-Jacques Degroof has supported various student organizations such as MIT's chapter of Engineers Without Borders.
Founded in 2002, Engineers Without Borders owes its existence to Dr. Bernard Amadei, who visited Belize in 2000 and found a Mayan community living without adequate clean water. After discussing the best way to tackle the issue with his colleagues, Dr. Amadei returned to Belize with a team of students to construct a water supply system.
Now Engineers Without Borders continues to supply clean water to communities around the globe and assists with other development needs, such as installing solar panels for electricity. The organization relies on the efforts of countless volunteers who work to enhance living conditions in impoverished communities. Volunteers come from a wide variety of backgrounds and range from students to skilled professionals.
An experienced business management educator and administrator, Jean-Jacques Degroof is a self-employed venture investor and entrepreneurship and innovation teacher who splits his time between Brussels, Belgium, and Boston, Massachusetts. He has been involved with the Charité Entrepreneurship Summit in Berlin, Germany, for five years. From 2013 to 2015, Jean-Jacques Degroof helped to organize this event as a member of the Charité Entrepreneurship Summit Advisory Board.
In 2017, the event recognized the exceptional past and present support of the Berlin Institute of Health (BIH) by officially becoming the Charité BIH Entrepreneurship Summit. Another highlight of the 2017 event was a special overseas collaboration with the business leaders of Israel. As an official partner country, Israel enjoyed a special place among the bevy of countries showcasing talented professionals and startups at the Charité BIH Entrepreneurship Summit.
The 2017 Charité BIH Entrepreneurship Summit took place from May 8 to May 9 at the Berlin-Brandenburg Academy of Sciences and Humanities. Featured speakers at the event included Doron Abrahami, the minister for commercial affairs and head of the economic and trade mission at the Israeli Embassy in Berlin.
A mentor for young technology entrepreneurs, Jean-Jacques Degroof has enjoyed a successful career that spans the private and academic sectors. Graduating summa cum laude from the Catholic University of Louvain (UCL) in Belgium, he later earned his MS and PhD from the Massachusetts Institute of Technology. Jean-Jacques Degroof has served on various organization boards including that of the Centre of Technological Resources in Chemistry (Certech).
An independent nonprofit entity, Certech was founded in 1996 by UCL with financial backing from the Walloon region in Belgium and the European Union. UCL transferred to Certech, based in Seneffe, Belgium, three of its laboratories long known for ingenuity and industrial joint efforts in chemistry. Certect was primarily intended to assist in reviving chemical-related industries in Walloon and help in job creation.
As a contract research organization, Certech offers its expertise in problem-solving, analysis and measurement, and product and process development to small and large industrial companies. Aside from collaborating with chemical industry firms, it also provides its expertise to other fields including construction, personal care, automotive, and environmental. Over the course of 2016, it entered into 700 contracts involving 210 different enterprises and produced a 70:30 private-public income ratio.
An entrepreneur who advises young tech entrepreneurs, Jean-Jacques Degroof has taught entrepreneurship at several European business schools. A fellow of the Massachusetts Institute of Technology (MIT) Sloan School of Management, Jean-Jacques Degroof takes part in the school’s mentoring program.
The MIT Sloan Student-Alumni Mentoring Program connects students with alumni in a diverse array of industries. Both alumni and students create user profiles by uploading information on careers, areas of study, and other interests. The program suggests matches based on the profile data, thereby expediting students’ search for a compatible mentor.
Students benefit from one-on-one contact with their mentors, who offer advice, answer questions, and share their experiences. Conversely, mentors benefit from contact with students who have access to the innovative educational environment on the MIT campus. In this way, the MIT Sloan Student-Alumni Mentoring Program helps establish mutually beneficial relationships between alumni and the next generation of leaders.
A professor of entrepreneurship at various European business schools, Jean-Jacques Degroof enjoys mentoring young entrepreneurs in the technology sector. Jean-Jacques Degroof is also a former teaching assistant at the Massachusetts Institute of Technology (MIT) Sloan School of Management, and has remained affiliated with the MIT Industrial Performance Center (IPC) for many years.
Founded in 1992, IPC addresses and researches key questions facing firms, industries or regions related to building greater innovation capacity that can lead to benefits for all members of society. It regularly convenes key actors from the public, private and non-profit sectors to discuss those topics and their implications for the global economy.
IPC was created as part of the network of Alfred P. Sloan Foundation Industry Study Centers to further the research carried out by the MIT Commission on Industrial Productivity. This commission produced a widely distributed report titled Made in America: Regaining the Productive Edge (MIT Press, 1989), which laid out a blueprint for improving productivity in the U.S. manufacturing sector. Since its inception, the IPC has worked on a number of projects, including Unlocking Energy Innovation: How America Can Build a Low-Cost, Low-Carbon Energy System (2011) and Production in the Innovation Economy (2013).
Independent business venture investor Jean-Jacques Degroof teaches courses on entrepreneurship and innovation management at various European business schools. Jean-Jacques Degroof trained at the MIT Sloan School of Management and holds memberships with its Dean’s Circle as one of the school’s alumnus contributors.
The Dean’s Circle provides recognition to MIT Sloan alumni and friends for charitable contributions to the MIT Sloan Annual Fund made during any fiscal year. A flexible source of funding for many of the school’s foundational programs, the Annual Fund supports initiatives that focus on education, research, innovation, and programs such as student fellowships and Action Learning Labs. Members of the Dean’s Circle consist of alumni donors with a dedication to shaping the future, fostering innovation, and improving opportunities for MIT Sloan faculty and students.
In order to become a member of the Dean’s Circle, donors must contribute at least $2,500 to the Annual Fund each year. Members will receive a variety of benefits depending on the size of their gift, including access to MIT community events and exposure to research and through leadership. Additional benefits may range from invitations to speaker series to admittance to faculty and Dean’s Circle exclusive receptions.